Click here to view Prescribing Information Find a Dermatologist in your area who can help determine whether acne treatment is right for you

Click here to see Important Safety Information for ZIANA Gel.
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The Medicis MediSAVE Program limits eligible patient out-of-pocket costs to $20 or less for each 60 g tube of ZIANA Gel (up to 3 prescription fills)

About Acne

What is acne?

Acne is a skin condition that causes blemishes to form, most noticeably on the face. Better known as zits or pimples, these blemishes are commonly the result of hormones increasing sebum production that - along with other substances - can clog the skin's pores. Acne usually begins around puberty when hormonal changes cause oil glands to kick into high gear and increase sebum production, but breakouts can occur at other times for a variety of reasons.2

What's the cause of acne?

Just under your skin, there are thousands of oil-producing glands called sebaceous glands. Normally, oil passes through pores to the skin's surface. But when dead skin cells, bacteria, or excessive oil blocks the pore, acne can form. This blockage causes oil to pool within the pore and allows acne-causing bacteria (P. acnes) to grow. These bacteria often cause inflammation, making the pimple red, sore, and occasionally full of pus.2

What are some common myths about acne?

Almost everyone has heard that certain foods like chocolate and soft drinks can cause acne: not true. Acne isn't the result of poor hygiene either. Things like stress, fatigue, humidity, cosmetics, and menstrual cycles can aggravate acne, but they don't cause it. In addition, acne tends to run in families.2

When should I see a dermatologist?

Most teenagers have at least an occasional whitehead, blackhead, or pimple. Having a few zits here and there is normal, and can usually be managed with over-the-counter medications. However, more than 40% of teens will have acne conditions that require treatment by a doctor.2

How is it treated?

There is no instant cure for acne. Don't get discouraged when a popular product hasn't worked for you. People are different, and sometimes a treatment that works for one person won't work for another. Usually, a physician-directed course of treatment can take up to 12 weeks to produce results. Even after some initial success, breakouts can still occur, and subsequent treatments may be needed to keep acne under control.2 Your dermatologist will be able to choose a treatment regimen that's best for your skin type.

What types of treatments are available?

There are a number of treatments available for people with acne. For patients with only occasional breakouts, something like an over-the-counter benzoyl peroxide or salicylic acid acne treatment may do the job. However, those with moderate to severe acne might need a prescription medication. And for those with cystic acne - hard, painful bumps under the skin - something stronger may be needed.2 Ask your dermatologist about the severity of your acne and what type of product is right for you. If you do not have a dermatologist, click here to find a doctor near you.

If I've got acne, how should I care for my skin?

  • Wash your face with a mild cleanser in the morning, at night, and after heavy exercise. Your dermatologist can recommend a cleanser for you.
  • Avoid excess scrubbing because it might increase irritation. Try to keep your hands, hair, and objects like straps, hats, and phones away from your acne.
  • Don't touch or squeeze pimples. This can spread the infection and cause permanent scarring.
  • Avoid using oily cosmetics. Look for noncomedogenic (oil-free) cosmetics like foundation, blush, eye shadow, moisturizers, and hair-care products. Also, be sure to completely remove makeup before bed.
  • Eat a balanced diet and maintain good hygiene.
  • Be patient. Your acne may get worse before it gets better, and it usually takes at least a month to evaluate your treatment's effectiveness.
  • Follow your dermatologist's instructions and use medications as directed.2
Cause of acne
Indication for ZIANA Gel

ZIANA Gel is used on the skin for treatment of acne in patients 12 years or older.

Important Safety Information for ZIANA Gel
  • The most commonly reported adverse events were inflammation of the nose and throat, throat pain, dry skin, cough, and sinus inflammation.
  • Stop ZIANA Gel and call your doctor if you develop watery or bloody diarrhea, or if your skin becomes very red, swollen, blistered, or crusted.
  • Avoid excessive exposure to the sun, cold, and wind. Weather extremes can dry and burn the skin. Always use a sunscreen on skin treated with ZIANA Gel, even on cloudy days. Use other protective clothing, such as a hat, when you are out in the sun. Avoid the use of sunlamps and tanning booths. If your face becomes sunburned, stop treatment until your skin has healed.
  • Do not get ZIANA Gel in your eyes or mouth, on your lips, on the corners of your nose, or on open wounds.
  • Do not use ZIANA Gel if you have Crohn's disease, ulcerative colitis, or have developed colitis with past antibiotic use.
  • Avoid medicated or abrasive soaps and cleaners, soaps and cosmetics that have a strong drying effect, and skin products that contain alcohol, astringents, spices, or lime.
  • Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Click to view eligibility criteria for the Medicis MediSAVE Program card.