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ZIANA® (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel Logo
Image of a ZIANA® Gel tube and rebate form that reads 'Receive up to $35 rebate on ZIANA® Gel.'
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ZIANA Gel
An effective combination treatment for mild, moderate and severe acne vulgaris.

ZIANA Gel is indicated for the topical treatment of acne vulgaris in patients 12 years or older.1 The effective treatment of your acne depends on the type and severity of your condition (see About Acne).

By combining an antibiotic (clindamycin) with a retinoid (tretinoin), ZIANA Gel provides two active ingredients in one effective treatment option.3 ZIANA Gel is the first and only product to offer these demonstrated acne fighters in one easy-to-use gel.2 For more information, see About ZIANA Gel and ZIANA Gel Important Safety Information. Ask your dermatologist if ZIANA Gel is right for you.

Why ZIANA Gel?

Smooth, water-based gel.
Convenient, once-a-day dosing.
Large, economical 60 g tube.
Two active ingredients for one price.
$25 or less co-pay for a 60-gram tube!

ZIANA Gel is the only product of its kind. If your pharmacist tries to substitute, call 877-799-4262.

Important Safety Information for ZIANA Gel
ZIANA Gel is used on the skin for treatment of acne in patients 12 years or older.

  • The most commonly reported adverse events were inflammation of the nose and throat, throat pain, dry skin, cough, and sinus inflammation.
  • Stop ZIANA Gel and call your doctor if you develop watery or bloody diarrhea, or if your skin becomes very red, swollen, blistered, or crusted.
  • Avoid excessive exposure to the sun, cold, and wind. Weather extremes can dry and burn the skin. Always use a sunscreen on skin treated with ZIANA Gel, even on cloudy days. Use other protective clothing, such as a hat, when you are out in the sun. Avoid the use of sunlamps and tanning booths. If your face becomes sunburned, stop treatment until your skin has healed.
  • Do not get ZIANA Gel in your eyes or mouth, on your lips, on the corners of your nose, or on open wounds.
  • Do not use ZIANA Gel if you have Crohn’s disease, ulcerative colitis, or have developed colitis with past antibiotic use.
  • Avoid medicated or abrasive soaps and cleaners, soaps and cosmetics that have a strong drying effect, and skin products that contain alcohol, astringents, spices, or lime.
  • Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.


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ZIANA is a registered trademark of Medicis Pharmaceutical Corporation. © 2010 Medicis, The Dermatology Company. All rights reserved.

By following the link, you will be leaving this Medicis product website. Medicis did not prepare the information on the linked websites, nor does it monitor or endorse the content of the linked website. Medicis is not responsible for the information found on the linked site, including any information that may be about Medicis. The links are provided only as citations and aids to help you locate and identify other Internet resources that may be of interest. These links are not intended to state or imply that Medicis has sponsored, approved, or adopted any materials on the linked website or that it is legally authorized to use any trade name, trademark, logo, seal or copyrighted information reflected in the linked site.

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By following the link, you will be leaving this Medicis product website. Medicis did not prepare the information on the linked websites, nor does it monitor or endorse the content of the linked website. Medicis is not responsible for the information found on the linked site, including any information that may be about Medicis. The links are provided only as citations and aids to help you locate and identify other Internet resources that may be of interest. These links are not intended to state or imply that Medicis has sponsored, approved, or adopted any materials on the linked website or that it is legally authorized to use any trade name, trademark, logo, seal or copyrighted information reflected in the linked site.

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